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Integration of expression data in genome-scale metabolic network reconstructions
2012
Frontiers in Physiology
With the advent of high-throughput technologies, the field of systems biology has amassed an abundance of "omics" data, quantifying thousands of cellular components across a variety of scales, ranging from mRNA transcript levels to metabolite quantities. Methods are needed to not only integrate this omics data but to also use this data to heighten the predictive capabilities of computational models. Several recent studies have successfully demonstrated how flux balance analysis (FBA), a
doi:10.3389/fphys.2012.00299
pmid:22934050
pmcid:PMC3429070
fatcat:ayxykl6vvfhv7c7zqk3xfxmpre