THE EFFECTS OF CHLORPROMAZINE ON CEREBRAL CIRCULATION AND METABOLISM

TOYOZO AIZAWA, YUICHIRO GOTO, YOSHIAKI TAZAKI, SHOICHI HAMAYA, KOKI MAKINO
1956 The Keio Journal of Medicine  
Since chlorpromazine appeared in the clinical field as the chief drug of the artificial hibernation therapy, many physicians were interested in its specific phamacologic and clinical actions, and now it has been used not only in the field of surgery and psychiatry but also in the every clinical field. Especially its action for the central nurvous system is remarkable i.e., the action of hypnotism, calmness, antispasm, control of vomit, alleviation of fever and etc.(1) And then it is said that
more » ... has the action of the pharmacologic lobotomy and the inhibitory action of thalamus. Therefor it is interesting to measure the effects of this drug on the cerebral circulation and metabolism, in a sense to observe its working mechanism. The hypotensive state and the
doi:10.2302/kjm.5.205 fatcat:qhkaczlhrnfnlhwzdlr7bnyoey