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The modulating effects of Korean ginseng saponins on ovarian functions were investigated in immature rats superovulated with pregnant mare serum gonadotropin (PMSG). A single dose of 1 mg (0.1 ml/head) of Korean ginseng total saponin (GTS), Korean ginseng protopanaxatriol saponin (GPT), Korean ginseng protopanaxadiol saponin (GPD), or ginsenoside-Rb 1 (Gin-Rb 1 ) was intravenously injected via jugular vein catheter three times at 1 h (early follicular phase), 25 h (middle follicular phase), anddoi:10.1248/bpb.26.1574 pmid:14600404 fatcat:ruhtvrsjmzb3dd33gan3l3ze6i