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A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary
1997
Development
Germline stem cells play a pivotal role in gametogenesis; yet little is known about how they are formed, how they divide to self-renew, and how these processes are genetically controlled. Here we describe the self-renewing asymmetric division of germline stem cells in the Drosophila ovarian germline, as marked by the spectrosome, a cytoplasmic structure rich in membrane skeletal proteins. The ontogeny of the spectrosome marks the lineage of germline stem cells. We identified two new groups of
pmid:9199372
fatcat:46kdoe5uwbcm7k7dclkgqmkcwu