Nevus lipomatosus superficialis is an uncommon cutaneous hamartoma that is characterized by the presence of adipose tissue within the reticular dermis. We describe a 15-year-old boy with a three-year history of the classic type of nevus lipomatosus superficialis, which presented as linear arrays of soft, cerebriform papulonodules and plaques in the right inguinal fold. Investigation for chromosomal aberrations and dysregulation of Wnt signaling may provide insights into the pathogenesis of this

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... hamartoma. Treatment is usually with surgical excision although successful use of other modalities has been described. Case synopsis History: A healthy 15-year-old boy presented to the Pediatric Dermatology Clinic at the Skin and Cancer Unit for evaluation and management of exophytic plaques in the right inguinal fold. These asymptomatic lesions had been slowly enlarging since they first appeared at 12 years of age.