More neuropeptides in C. elegans

Nektarios Tavernarakis
2002 Genome Biology  
A genome-wide scan has revealed multiple conserved groups of neuropeptide genes in the nematode Caenorhabditis elegans Significance and context Much synaptic signaling in the nervous system is facilitated by specialized peptidergic neurotransmitters called neuropeptides. Neuropeptides function in neurotransmission primarily by modulating synaptic signaling through other, small-molecule, neurotransmitters, and exert their function through seven-span transmembrane receptors, although a sodium
more » ... though a sodium channel that can be directly gated by the neuropeptide FMRF has been identified inthe snail Helix lucorum. Neuropeptides thus appear also to act as fast neurotransmitters.
doi:10.1186/gb-2002-3-2-reports0010 fatcat:l3hfhuvrfjfutgzhbj2g2bio4y