Morphoquantitative Analysis of the Intraepithelial Neoplasic Uterine Cells by Computer Image System

Jacqueline Silva Brito Lima, Alexandre Motta Bittencourt, Carlos Eduardo de Queiroz Lima, Diógenes Luis da Mota, Ana Maria de Ataíde Romaguera, Luiz Lúcio Soares da Silva
2008 International Journal of Morphology  
Morphoquantitative analysis of the intraepithelial neoplasic uterine cells by computer image system. Int. J. Morphol., 26(1):93-98, 2008. SUMMARY: The purpose of the present research was to detect the DNA variations by Feulgen stained chromatin and the packing degree of the cervical chromatin in the clinical cases of human uterine carcinomas. Scanning microphotometry was carried out on slides prepared from block Feulgen-stained. Accurate control procedures were performed using normal human cell
more » ... nuclei. The cervical cells was morphometric studied using the Image Lab System for citologic classification. The overall diagnostic accuracy for neoplasia type I (CIN I) and type II (CIN II), demonstrated by stain interpetration values of a sensitive detection of DNA neuroploidy and a significant difference between the two groups in scanning static cytophotometry.
doi:10.4067/s0717-95022008000100016 fatcat:ib4z4wmwynggdl7bshjkhqqoae