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A n kylosing spondylitis is a common inflammatory rheumatic disease. Both susceptibility to and clinical manifestations of the disease are highly heritabl e, Although some ge n e s , n o t ably HLA-B27,have been implicated in susceptibility to the disease, the genetic of the condition are complex and many more genes involved in the condition await discovery.doi:10.1097/bor.0b013e3283364483 pmid:20084006 fatcat:wdw4pm2cx5h6zkbimwehe3ppbi