Osteoporosis and male age-related hypogonadism: role of sex steroids on bone (patho)physiology

V Rochira, A Balestrieri, B Madeo, L Zirilli, A R M Granata, C Carani
2006 European Journal of Endocrinology  
Male age-related bone loss is caused, at least in part, by hypogonadism that occurs with advancing age. The study of the effects of sex steroids on bone physiology in men has recently highlighted the central role of estrogens on bone pathophysiology. This review focuses on particular aspects of bone physiology and pathophysiology in aging men, noting both the similarities to and the differences from female counterparts. In particular, the role of sex steroids on bone sexual dimorphism in health
more » ... imorphism in health and disease has been analyzed.
doi:10.1530/eje.1.02088 pmid:16452530 fatcat:rt6cs73mmrcg7li7qq7stsjm64