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Pinacidil suppresses contractility and preserves energy but glibenclamide has no effect during muscle fatigue
2000
American Journal of Physiology - Cell Physiology
Pinacidil suppresses contractility and preserves energy but glibenclamide has no effect during muscle fatigue. Am. J. Physiol. Cell Physiol. 278: C404-C416, 2000.-The effects of 10 µM glibenclamide, an ATP-sensitive K ϩ (K ATP ) channel blocker, and 100 µM pinacidil, a channel opener, were studied to determine how the K ATP channel affects mouse extensor digitorum longus (EDL) and soleus muscle during fatigue. Fatigue was elicited with 200-ms-long tetanic contractions every second.
doi:10.1152/ajpcell.2000.278.2.c404
pmid:10666037
fatcat:oeo7aqscevgjnmfun4pqyijw34