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LUM is the hub gene of advanced fibrosis in nonalcoholic fatty liver disease patients
Clinics And Research in Hepatology and Gastroenterology
Advanced fibrosis in nonalcoholic fatty liver disease (NAFLD) is associated with a poor prognosis. The genetic factors contributing to fibrosis in NAFLD have been described. However, the genetic mechanism and hub genes of advanced fibrosis have not been elucidated to date. In this study, we performed a weighted gene coexpression network analysis (WGCNA) to identify the hub genes related to advanced fibrosis in NAFLD. The datasets GSE89632 and GSE31803 of NAFLD patients were selected from thedoi:10.1016/j.clinre.2020.04.006 pmid:32386798 fatcat:wk5n72oxfnbfnmz2iogahbjo44