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In many patients with brain metastases, the primary therapeutic aim is symptom palliation and maintenance of neurologic function, but in a subgroup, long-term survival is possible. Local control in the brain, and absent or controlled extracranial sites of disease are prerequisites for favorable survival. Stereotactic radiosurgery (SRS) is a focal, highly precise treatment option with a long track record. Its clinical development and implementation by several pioneering institutions eventuallydoi:10.1186/1748-717x-9-155 pmid:25016309 pmcid:PMC4107473 fatcat:f2hmduc5k5f63a2d4ifnkzvg3a