This Journal of Informetrics special issue aims to improve our understanding of the structure and dynamics of science by reviewing and advancing existing conceptualizations and models of scholarly activity. Several of these conceptualizations and models have visual manifestations supporting the combination and comparison of theories and approaches developed in different disciplines of science. Subsequently, we discuss challenges towards a theoretically grounded and practically useful science of

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... science and provide a brief chronological review of relevant work. Then, we exemplarily present three conceptualizations of science that attempt to provide frameworks for the comparison and combination of existing approaches, theories, laws, and measurements. Finally, we discuss the contributions of and interlinkages among the eight papers included in this issue. Each paper makes a unique contribution towards conceptualizations and models of science and roots this contribution in a review and comparison with existing work.