Prevention of Staphylococcal Bacteriophage Activity by Antigen A Precipitins in Human Sera

R. Russell Martin, Arthur White
1968 Journal of Bacteriology  
Antigen A precipitins in human sera prevented plaque formation and propagation of staphylococcal bacteriophages. Over 20% of total IgG was removed from human sera by absorption with staphylococci containing antigen A. The specific precipitating antibody in rabbit antisera forrred lines of idenity with antigen A precipitins in lower dilutions of human sera but formed lines of nonidenity with antigen A precipitins in higher dilutions of the same sera, suggesting both specific and nonspecific
more » ... en A precipitins in human sera. The specific and nonspecific antigen A precipitins in human sera may prevent the in vivo activity of staphylococcal bacteriophages which have been demonstrated previously in animals whose sera do not contain either specific or nonspecific antigen A precipitins.
doi:10.1128/jb.95.6.2177-2181.1968 fatcat:3pr4ha64c5h33lyjti3yq3zsei