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Archives of Surgery
O b je c tiv e s : To examine the effects of perioperative ad ministration of fluorouracil on healing variables of in testinal anastomoses and to explore ways to promote re pair under these conditions. D esign: Seven-day, prospective randomized experimen tal trial. S e ttin g : Animal research laboratory. A n im a ls : Male young-adult Wistar rats after resection and anastomosis of both ileum and colon. In te rve n tio n s: Random assignment to groups receiv ing placebo, daily fluorouracil (20doi:10.1001/archsurg.1995.01430090045017 pmid:7661680 fatcat:yg5nfhbiuzf53pfakq2wg3wybi