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The zinc oxide (ZnO) nanowire arrays on the indium tin oxide (ITO) glass substrates were fabricated by using the two-step hydrothermal method. A high transmittance ~92% of ZnO nanowire arrays on ITO substrate in the visible region was obtained. It was observed that the liquid crystal (LC) directors were aligned vertically to the (ZnO) nanowire arrays. The properties of ZnO nanowire arrays as vertical liquid crystal (LC) alignment layers and their applications for hybrid-aligned nematic LC modes were investigated in this work.doi:10.1364/oe.21.029277 pmid:24514480 fatcat:cjpebrk7xjdy7fihzvnwjwf72u