Evaluation of the risk factors of radio-dermatitis after breast-conserving surgery [post]

2020 unpublished
KEYWORDS Breast cancer, post-breast-conserving surgery, radiotherapy, risk factors of radiodermatitis (RD) 2 Abstract Background The morbidity of breast cancer has been ranked first among female cancers worldwide and increased by 2% each year in these ten years [1] . Although China as a country with a relatively low incidence of breast cancer compares to other countries, the rapid growth rate of breast cancer is still worth Method A total of 521 patients with breast cancer diagnosed in the
more » ... agnosed in the Union Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology and underwent breast conserving surgery (lumpectomy plus local radiotherapy) were selected, to investigate demographic data, disease data, treatment data and behavior data. Using univariate and multivariate logistic regression method to analyze the risk factors of RD after radiotherapy. Results The variable factors of age ≤40 years old, whiter skin, treatment time in summer, BMI≥25, local thermal therapy, sun exposure, skin scratching and bra wearing are the risk factors of radiodermatitis, while the affected limb akimbo in daytime and elevating the affected limb in sleep are the protective factors of radio-dermatitis. Conclusion This study aims to observe the situation of post-radiotherapy RD after breast-conserving surgery in patients with breast cancer, analyze the risk factors related to patients and treatment, and provide the relevant clinical basis for reducing and preventing the occurrence of RD after breast-conserving surgery.
doi:10.21203/rs.3.rs-15417/v1 fatcat:5zy2guyvpbhi7lb3hekcyfb7pq