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Assessment of the anticancer activity of Caryophyllene oxide against breast cancer cell line and related genetic alterations: In vitro study
Journal of Environmental Sciences. Mansoura University
Article history: Received Received in revised form Accepted The aim of this work was to identify the anticancer activity of Caryophyllene oxide (CPO) against MCF7 cell lines. CPO as phytochemical terpenoids is a chemoprevention derivative enhances breast cancer growth inhibition and proliferation. The cytotoxicity of CPO against breast cancer cells (MCF-7) was concentration dependent and the inhibitory concentration (IC 50 ) of CPO was 24 µM/ ml. Also, toxicity of CPO was accompanied with thedoi:10.21608/joese.2019.158392 fatcat:usiydhfaajcz5hglntm3j62v5y