Approach to Ventricular Arrhythmias in the Pediatric Intensive Care Unit [chapter]

Jong-Hau Hsu, Jiunn-Ren Wu, Zen-Kong Dai, I-Chen Che
2012 Cardiac Arrhythmias - New Considerations  
Approach to Ventricular Arrhythmias in the Pediatric Intensive Care Unit 293 3.2 Hypertrophic cardiomyopathy P a t i e n t s w i t h h y p e r t r o p h i c c a r d i o m y o p a t h y c o m p r i s e a s u b g r o u p w i t h m y o c a r d i a l disease that is prone to ventricular arrhythmias. Left ventricular outflow tract obstruction may cause coronary artery insufficiency and myocardial ischemia, thus resulting in ventricular arrhythmias. Microscopically, hypertrophic cardiomyopathy shows
more » ... rdiomyopathy shows disorganization of the cardiac muscle cells, a substrate for arrhythmia. Indeed, this microscopic finding seems to put these patients at risk regardless of the degree of outflow tract obstruction. Non-sustained ventricular tachycardia is common in children with hypertrophic cardiomyopathy. Clinical risk factors of sudden death include family history of cardiac arrest, increased QRS duration, myocardial bridging of the left coronary artery, increased QT dispersion, ventricular wall thickness, exercise-induced hypotension, and syncope.
doi:10.5772/25402 fatcat:q5ukhuiiqrgbdacloffyzvxsri