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3H-Thymidine labelling index (TLI) as a marker of tumour growth heterogeneity: evaluation in human solid carcinomas
Many studies deal with the analysis of cell kinetic, cytogenetic, biochemical and molecular cell biology parameters to identify prognostic factors relating to tumour growth but all methods use only a small part of the total tumour mass. This study is devoted to the analysis of the heterogeneity of the growth of human solid tumours assaying proliferative activity by means of 3H-thymidine labelling index (TLI) in a fixed number of samples collected in different areas of the lesion (larynx anddoi:10.1046/j.1365-2184.1997.00074.x pmid:9375024 fatcat:pnwiiz2umfecfdgfmov35yp4fe