Update on National Toxicology Program (NTP) Assays with Genetically Altered or "Transgenic" Mice

John R. Bucher
1998 Environmental Health Perspectives  
The NTP is evaluating sveral lines of genetic altered mice for possible use in identiing and assessing carcinogens. The NIEHSINTP programs and progress in this area were recently revieed by: the NTI Board of Scientific unslors (BSC). A number of comments and concerns were raised. This commentary summanres and responds to the BSC rview and offirs some thoughts on future direcdons for this line of resarch as well as posible ways lly altered ce might be ingated ito a comprehensive testn straegy.
more » ... ve testn straegy. Ky word alterative cancer assays, enecall altered mice, tsgenic mice, Ni? Board of Scientific Counelors Review. Environ HeakbP"epct 106: 619-621 (1998). [Online 2 Steber] hp:/epntl.niehs.niAgov/doks119981106p619-621 bwborla&srathd
doi:10.2307/3434087 fatcat:7v4smlwurffvnd6o5gyxulig2q