Workshop

2020 European psychiatry  
Although ICD-10 "acute and transient psychotic disorders" (ATPDs) are more common in developing countries than in developed ones, little is known about factors associated with the course and outcome of these conditions. This study examines the predictive strength of baseline clinical and demographic variables and the short-term outcome of ATPDs in a developmental country setting. Method: Retrospective study of all patients with a first episode ATPD attending the University College Hospital,
more » ... an, Nigeria between 2006 and 2011, and who had at least 1-year follow-up information available. Psychopathological symptoms were rated using the 5-factor model of the Positive and Negative Syndrome Scale (PANSS). Multivariate analyses were conducted to identify clinical and demographic outcome predictors. Results: Of the 52 patients with ATPDs (59.6% women; mean age 27.5 years), 33 (63.5%) did not develop another diagnosis on average over 4.8 years. Patients featuring polymorphic psychotic symptoms were less likely to change diagnosis than those with the acute schizophrenia-like presentation, who instead tended to progress mainly to schizophrenia in subsequent episodes. No baseline variable was found to be significantly associated with temporal stability of ATPDs. Multivariate analyses revealed that excitement/hostility was the only PANSS factor predicting diagnostic transition. Conclusion: These findings suggest that the diagnostic consistency of ATPDs is relatively high in Ibadan, and argue for prognostic differences among the ATPD subtypes. Conflicts of Interest: No
doi:10.1192/j.eurpsy.2020.12 fatcat:u7sa4mk7zzbx7c7djw2gzbk4le