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Computational approach towards Identification of Functional Mutations in Il-6 Cytokine Family and It's Putative Association with Head and Neck Squamous Cell Carcinoma
2019
International Journal of Dentistry and Oral Science
Objectives: The present study aimed to identify alterations in the IL-6 family to derive a putative association with HNSCC (head and neck squamous cell carcinoma). Subjects and Methods: Computational approaches have been used to find the functional mutation in the IL-6 family. The cBioportal database served as the primary source of data for analyzing the mutations. The TCGA (The Cancer Gene Atlas, Firehose legacy) dataset encompassing 504 samples of HNSCC patients were included in the study.
doi:10.19070/2377-8075-si02-06002
fatcat:yypsoigze5hu5ookthi6b2k6qq