Temporal metamaterials empower novel forms of wave manipulation with direct applications to quantum state transformations. In this work, we investigate vacuum amplification effects in anisotropic temporal boundaries. Our results theoretically demonstrate that the anisotropy of the temporal boundary provides control over the angular distribution of the generated photons. We analyze several single and multi-layered configurations of anisotropic temporal boundaries, each with a distinct vacuum

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... ification effect. Examples include the inhibition of photon production along specific directions, resonant and directive vacuum amplification, the generation of angular and frequency photon combs and fast angular variations between inhibition and resonant photon production.