CRONOS: the cross-reference navigation server

Brigitte Waegele, Irmtraud Dunger-Kaltenbach, Gisela Fobo, Corinna Montrone, H.-Werner Mewes, Andreas Ruepp
2008 Computer applications in the biosciences : CABIOS  
Cross-mapping of gene and protein identifiers between different databases is a tedious and time-consuming task. To overcome this, we developed CRONOS, a cross-reference server that contains entries from five mammalian organisms presented by major gene and protein information resources. Sequence similarity analysis of the mapped entries shows that the cross-references are highly accurate. In total, up to 18 different identifier types can be used for identification of cross-references. The
more » ... of the mapping could be improved substantially by exclusion of ambiguous gene and protein names which were manually validated. Organismspecific lists of ambiguous terms, which are valuable for a variety of bioinformatics applications like text mining are available for download. Availability: CRONOS is freely available to non-commercial users at
doi:10.1093/bioinformatics/btn590 pmid:19010804 pmcid:PMC2638938 fatcat:asaoknrz6nc2ndfcsltmyv7isi