The aim of the study is to evaluate the prevalence of multi drug resistant tuberculosis in Khammam district. The objective is to create awareness among healthcare personnel and patients regarding MDR-TB. The study was conducted over a period of six months, i.e., December 2016-June 2017. Result: A total of 54 MDR-TB cases were studied. According to age groups 32 subjects are in the young and middle age groups which comprise a total of about 59.1 whereas in early age there are 6.8%. Many

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... are considered in this study out of which alcohol was rated as highest because 59.2% subjects in the study were alcoholics. A total of 31.8% smokers was found out. Diabetes was also a variation with 27.8% subjects suffering. A total of 18.5% of subjects was suffering from TB with HIV. Conclusion: The study reveals that the subjects suffered from resistance to category-I drugs and hence they are transferred to category-IV drugs. Tuberculosis is a disease that mainly affects the people of age groups 20-40 and is more prevalent in males than that of females. Variables like alcohol consumption rated as highest risk factor, followed by smoking, diabetes and HIV respectively.