Caloinophyllin A, a new chromanone derivative from Calophyllum inophyllum roots

Sasa Ponguschariyagul, Jirapast Sichaem, Suttira Khumkratok, Pongpun Siripong, Kiattisak Lugsanangarm, Santi Tip-Pyang
2018 Figshare  
A new chromanone derivative, namely caloinophyllin A (1), along with eight known compounds (2–9), nobiletin (2), pentamethylquercetin (3), 3,5,7,4′-tetramethoxyflavone (4), 5,7,4′-trimethoxyflavone (5), 1,5-dihydroxyxanthone (6), 1,8-dimethoxy-2-hydroxyxanthone (7), 1,6-dihydroxy-7-methoxyxanthone (8) and 4-methoxycaffeic acid (9) were isolated from the roots of Calophyllum inophyllum. The structures of all the isolated compounds (1–9) were fully characterised using spectroscopic data, as well
more » ... s comparison with the previous literature data. In addition, the quantum chemical calculation has been used to confirm the conformation of 1. Moreover, all isolated compounds were assessed for their in vitro cytotoxicity against five human cancer cell lines.
doi:10.6084/m9.figshare.5802774 fatcat:xfgydn7syfgn5oxstmk5k4vw7y