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Journal of Virology
The Tax protein of human T-cell leukemia virus type 1 (HTLV-1) is a potent activator of viral transcription. Tax also activates the expression of specific cellular genes involved in the control of T-lymphocyte growth via effects on cellular transcription factors, including members of the NF-B/cRel family. Immunocytochemistry and electron microscopy were used to characterize the intracellular localization of Tax and identify cellular factors which are the potential targets for itsdoi:10.1128/jvi.71.5.3484-3497.1997 fatcat:2aygonlzjjdz3akvse3k4nwayq