WS1-1-1 Nitrogen-Containing Bisphosphonates Inhibit the Growth of Renal Cell Carcinoma Cells(Renal Cell Cancer)

Naohiro Fujimoto, Bin Han, Masayoshi Nomura, Tetsuro Matsumoto
2008 The Japanese Journal of Urology  
Objectives] Originally, BPs were developed as a drug for bone diseases, However, recent studies demonstrated that the 3rd generation nitrogen-containing bisphosphonates (BPs) induce apoptosis in not only osteoclasts, but also several types of cancer cells and have an anti-cancer activities. In the present study, we investigated the effects of NBPs on the growth of renal cancer cells, [Materials and Methods] 1 ) BPs: incadronate (IC}. zoledronic acid (Zol), 2) RCC cells:
doi:10.5980/jpnjurol.99.142_1 fatcat:d7h37lntyfcwfexzut3vogjopa