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HOCOMOCO: a comprehensive collection of human transcription factor binding sites models
2012
Nucleic Acids Research
Transcription factor (TF) binding site (TFBS) models are crucial for computational reconstruction of transcription regulatory networks. In existing repositories, a TF often has several models (also called binding profiles or motifs), obtained from different experimental data. Having a single TFBS model for a TF is more pragmatic for practical applications. We show that integration of TFBS data from various types of experiments into a single model typically results in the improved model quality
doi:10.1093/nar/gks1089
pmid:23175603
pmcid:PMC3531053
fatcat:eawcgj6w6nhlrhlfjydkvyl32i