Effect of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 maternal loads on maternal and fetal vitamin D metabolite levels in the rat

Charlyne REBUT-BONNETON, Josiane DEMIGNON, Leonor CANCELA, Livia MIRAVET
1985 Reproduction nutrition development (Print)  
To cite this version: Charlyne Rebut-Bonneton, Josiane Demignon, Leonor Cancela, Livia Miravet. Effect of 25hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 maternal loads on maternal and fetal vitamin D metabolite levels in the rat. Reproduction Nutrition Développement, 1985, 25 (3), pp.583-590. hal-00898300 Effect of 25-hydroxyvitamin D 3 and 1,25-dihydroxyvitamin D 3 maternal loads on maternal and fetal vitamin D metabolite levels in the rat. Summary. Two groups of female rats were used to
more » ... stigate vitamin D metabolism in the pregnant animals and in their fetuses. In the first group, 3 wg of 25-hydroxyvitamin D 3 (25-OH-D 3 ) per kg of body weight were injected into intact or nephrectomized (NX) pregnant rats 3 h before sacrifice on day 21 of pregnancy ; in the second group, 2 and 6 ng, respectively, of 1,25-dihydroxyvitamin D 3 (1,2510H1 2 D 3 ) per day were infused
doi:10.1051/rnd:19850410 fatcat:sn4ckgscibfu7oszshpqz73dfy