Evaluation of Urinary Calcium Creatinine Ratio in Pre-Eclampsia

Indu Prasad
2016 National Journal of Laboratory Medicine  
Hypertensive disorder complicates the pregnancy. The exact aetiology of hypertensive disorders of the pregnancy is still unknown and management is controversial. Aim: To evaluate the role of urinary calcium creatinine (CCR) as an marker in early diagnosis of pre-eclampsia. Materials and Methods: Urinary calcium creatinine ratio was determined in a random sample of urine in100 patients of pre-eclampsia (Study group) and 100 normotensive pregnant (Control group) patients of gestational age 20-36
more » ... eeks. Cut off value for CCR was taken as ≤ 0.04. Comparative study was done by using chi-square test. Results: In study group, 89% of the cases had urinary CCR ≤ 0.04. Similarly, amongst the controls only 6% of the cases had CCR ≤ 0.04. Statistically, CCR as high risk factor for early diagnosis of pre-eclampsia was significant (p<0.001 and 'r' = 0.169). Conclusion: The result showed lower urinary calcium excretion and low CCR in pre-eclamptic patients than normotensive pregnant women. AIM To evaluate calcium: creatinine ratio for the early diagnosis of pre-eclampsia so as to avoid maternal and fetal morbidity and mortality in the society.
doi:10.7860/njlm/2016/17110.2102 fatcat:firbhykhgfgmhofoxoamkzyo6y