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Synopsis Four nitrofurans were compared for their effect on carcinogenesis induced by 4-(dimethylamino)azobenzene (DAB). The nitrofurans tested were 2-(2-furyl)-3- , 5-nitro-2-furaldehyde semicarbazone (N3), and 5-morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone (N4). Male Donryu rats were maintained on a diet containing 0.06% DAB and 0.2% of a nitrofuran until they consumed 1g of DAB (about 3.5 months), and succeedingly on a basal diet for 1 month. The liver of these animals wasdoi:10.20772/cancersci1959.62.6_479 fatcat:wak5qdzsgrbepbepah4lrfvzii