An evaluation of myocardial fatty acid and glucose uptake using PET with [18F]fluoro-6-thia-heptadecanoic acid and [18F]FDG in Patients with Congestive Heart Failure

M Taylor, T R Wallhaus, T R Degrado, D C Russell, P Stanko, R J Nickles, C K Stone
2001 Journal of Nuclear Medicine  
Understanding the metabolic consequences of heart failure is important in evaluating potential mechanisms for disease progression and assessing targets for therapies designed to improve myocardial metabolism in patients with heart failure. PET is uniquely suited to noninvasively evaluate myocardial metabolism. In this study, we investigated the kinetics of 14(R,S)-[18F]fluoro-6-thia-heptadecanoic acid (FTHA) and [18F]FDG in patients with stable New York Heart Association functional class III
more » ... tional class III congestive heart failure and a left ventricular ejection fraction of no more than 35%.
pmid:11197981 fatcat:bwomqfnth5fclhprwh46ix6k3i