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Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics

Noor Haslinda Noor Hashim, Jalifah Latip, Alfi Khatib
2016

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The metabolites of Clinacanthus nutans leaves extracts and their dependence on drying process were systematically characterized using H nuclear magnetic resonance spectroscopy (NMR) multivariate data analysis. Principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) were able to distinguish the leaves extracts obtained from different drying methods. The identified metabolites were carbohydrates, amino acid, flavonoids and sulfur glucoside compounds. The major
more » ... tabolites responsible for the separation in PLS-DA loading plots were lupeol, cycloclinacosides, betulin, cerebrosides and choline. The results showed that the combination of H
doi:10.1063/1.4966753 fatcat:ow7hrp4eerfm5kuq7ry7meqcm4
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Noor Haslinda Noor Hashim, Jalifah Latip, Alfi Khatib. "Metabolite profiling of Clinacanthus nutans leaves extracts obtained from different drying methods by 1H NMR-based metabolomics." (2016)