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Aim of current study was to analyse major amputation occurring in patients with diabetic foot complication through the new principle and practice of diabetic foot. Methods: A 5 year retrospective study was done in a single surgical unit in department of surgery of St John's medical college, Bangalore, India. Results: 26 patients were included in this study. 76.9% of the patients who underwent major amputation had type 1 diabetic foot complications. Infected ulcers were the most common cause fordoi:10.5455/2349-2902.isj20150205 fatcat:g7uerei4hrdzjgqpts5qofhzey