The world distribution of amoebic liver abscess should parallel that of amoebic infection. Unfortunately, its incidence of amoebic liver abscess varies throughout the world and large number of cases in developing countries. Pyogenic liver abscess constitute major bulk of hepatic abscess in western countries, they result from ascending biliary tract infection, hematogenous spread via portal venous system, generalized septicemia direct spread from intra-peritoneal infection. Pyogenic liver

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... constitute major bulk of hepatic abscess and they result from ascending biliary tract infection, hematogenous spread via portal venous system, generalized septicemia with involvement of liver by way of hepatic arterial circulation, direct spread from intra-peritoneal infection, other causes. Escherichia coli, klebsiella and streptococcus are most common organism followed by staphylococcus and pseudomonas. The mainstay of pharmacologic agent being metronidazole, which has been started since the time of diagnosis of liver abscess. Broad spectrum IV antibiotic was added in case of pyogenic liver abscess as an adjunct drug.