The emergence of diseases of maxillofacial area in childhood is caused both by the local factors and the presence of physical illness. The overall impact of these factors is subject to constant research in order to solve the problem of early diagnostics, adequate treatment and prevention of dental diseases. Today, much attention is paid to the studying of the rare, so-called orphan, diseases, one of which is cystic fibrosis. Cystic fibrosis is a genetic disorder that affects the respiratory and

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... digestive systems. It is based on a mutation of the gene and causes an infringement of ion exchange of the epithelial cells in exocrine glands of the body. The result of cystic fibrosis is disturbance of the structure and function of a protein that serves as a channel for the transport of chloride ions, changing the properties of the secretions and starts to develop of secondary disorders with damage to many systems and organs. Violation of exocrine glands, including salivary ones, impaired nutritional status of patients, vitamin deficiencies, osteoporosis cause the necessity of permanent use of antibacterial, enzymatic, hormonal methods which affect the oral health in the disease treatment. The aim of our study is to determine the prevalence and intensity of caries, dental individual level of caries intensity, level of oral hygiene and periodontal tissue status of the children with cystic fibrosis. We've used the methods for determining indicators, universal for the age of children, who have the same somatic diagnosis. To achieve this goal we've conducted clinical dental examination of 17 children aged 1, 5 to 16 years old with a diagnosis of cystic fibrosis. The level of prevalence and intensity of caries has been evaluated by the number of teeth, which are sealed, decayed and removed. To determine the state of oral hygiene index OHI-S (J. C. Green, J.R.Wermillion, 1964) in its component of plaque has been used. The condition of periodontal tissues has been evaluated as well on the basis of determination [...]