BACKGROUND: Grey's theories of BIS and BAS as well as the theories of Cloninger's temperament and character explain personality as biologically driven. Substance use can be explained a result of either inhibition or activation or combination of certain temperament and character according to these authors. Thus, it is acceptable to know the relationship between the variables of temperament and character and BIS/BAS in context of addiction. OBJECTIVE: To study the relationship between BIS/BAS

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... certain temperament and character of smoking and non-smoking university students. METHODS: Sample consisted of 25 smokers and 25 non-smokers university students with in the age group of 18 to 25 years. For the assessment the current study used BIS and BAS scales and TCI were used. RESULTS: Obtained result shows significant difference on Reward Dethe smoking group. Similarly on various domains of BAS such as drive, fun seeking and reward responsiveness the smoking group scored higher than the non smokers, BIS scores were found to be high in non smoking students. CONCLUSION: The need for understanding the relationship of TCI with BIS/BAS and how this influences and reinforces the tendency to smoke were implicated from this study.