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The aim of study was to investigate effect and possible mechanism of isoliquiritin on wound healing in scalded rats. The results show that at 24 h after the last administration, wound healing rate of isoliquiritin group was higher than that of model group (p=0.024). Compared with control group, thickness of epidermis and dermis in model group was thinner (p<0.001), and width of subdermal collagen fibers also decreased (p<0.001), inflammatory factors TNF-α, IL-6 and IL-1β in skin tissuedoi:10.17582/journal.pjz/20191010041047 fatcat:auhc463c2ffzfl2tppnokn5moe