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Comparative analgesic activity of leaves, stems and roots of Leucas linifolia spreng. (Lamiaceae) Full Paper Natural Products Natural Products

Sneha Anarthe, Rasika Bhalke, Rahul Morjaria, Bhushan Phapale, Sagar Pharande, An Journal
2008 unpublished

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Leucas linifolia; Lamiaceae; Hot plate method; Acetic acid induced writhing test. KEYWORDS ABSTRACT All the extracts from the leaves, stems and roots of Leucas linifolia (Lamiaceae) were investigated for their analgesic. The effect of pet ether, ethyl acetate and methanol extracts of various parts of Leucas linifolia on nociceptive response using hot plate method and writhing test in mice was examined. All the extracts of Leucas linifolia showed significant central and peripheral analgesic
more » ... ity in hot plate method and acetic acid-induced writhing test, respectively, at the dose of 50mg/kg intraperitoneally. Pet ether extract of stems of Leucas linifolia showed highest increase in reaction time in hot plate method while methanol extract of stems of Leucas linifolia showed more inhibitory effect on writhing induced by acetic acid as compare to extracts of leaves and root. 
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Sneha Anarthe, Rasika Bhalke, Rahul Morjaria, Bhushan Phapale, Sagar Pharande, An Journal. "Comparative analgesic activity of leaves, stems and roots of Leucas linifolia spreng. (Lamiaceae) Full Paper Natural Products Natural Products." (2008)