In Silico Target Identification and Validation for Antioxidant and Anti-inflammatory Activity of Selective Phytochemicals

Shikha Rana, Savita Dixit, Alok Mittal
2019 Brazilian Archives of Biology and Technology  
Phytochemicals present in plant extract include a number of biological active compounds which have shown promising antioxidant and anti-inflammatory activities in many animal studies. Present knowledge about the biochemical interactions of these compounds present in phytochemical extracts and target enzymes or proteins responsible for antioxidant and anti-inflammatory activity is limited. Present work is an attempt to identify and validate possible biological targets as enzymes or proteins
more » ... es or proteins involved in these targeted studies using molecular docking as computational method. IMPPAT: Indian HIGHLIGHTS  Phytochemicals from six local grown plants (pomegranate, lemon, wheatgrass, papaya, sheesham leaves, turmeric leaves) were used for the present study.
doi:10.1590/1678-4324-2019190048 fatcat:e5ahxrzk6bfttkbdcqifude57q