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Injury markers in two models of cerebral ischemia
Análisis comparativo de marcadores de lesión en modelos de isquemia cerebral focal y global en ratas
2013
Biomédica: revista del Instituto Nacional de Salud
Análisis comparativo de marcadores de lesión en modelos de isquemia cerebral focal y global en ratas
Spatio-temporal indicators of injury are essential for the study of neuropathological processes and for developing therapeutic approaches for stroke. This study sought to optimize the techniques of two cerebral ischemia models (focal and global) and to comparatively evaluate the progression of brain damage by analyzing markers of neurodegeneration. Wistar rats were subjected to temporary occlusion of the middle cerebral artery (t-MCAO) or four-vessel occlusion (4-VO), and surgical time,
pmid:24652140
fatcat:k2653suicbbrvplugae4l6rsoi