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Comparative animal study of the antinociceptive efficacy of lamotrigine and gabapentin for the management of pain
Acta Physiologica Hungarica
Pain relief using drugs with high efficacy provides significant improvement in the patients' lives. Drugs like lamotrigine (LTG) and gabapentin (GBP) have the ability to overcome the symptoms of neuropathic pain. Aim: The present study offers a comparative analysis of LTG and GBP efficacy in a rat model of nociceptive pain after single administration. Method: Sixty-three Wistar-Bratislava rats randomized into 7 groups were included: a control group treated with saline solution and 6 groupsdoi:10.1556/036.102.2015.4.3 pmid:26690028 fatcat:kbsbnsspnngwzi2npwlcxinwrm