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Creative Commons Attribution-Noncommercial-Share Alike Detailed Terms http://creativecommons.org/licenses/by-nc-sa/4.0/ The MIT Faculty has made this article openly available. Please share how this access benefits you. Your story matters. Abstract Biological hydrogels such as mucus, extracellular matrix, biofilms, and the nuclear pore have diverse functions and compositions, but all act as selectively permeable barriers to the diffusion of particles. Each barrier has a crosslinked polymericdoi:10.1039/c6nr09736g pmid:28580973 pmcid:PMC5841163 fatcat:2bdhnej6tjat5bmtnxrgfq3lxy