6 Diffusion tensor magnetic resonance imaging of myocardial disarray in hypertrophic cardiomyopathy

Rina Ariga, Elizabeth M Tunnicliffe, Sanjay G Manohar, Masliza Mahmod, Betty Raman, Stefan K Piechnik, Jane M Francis, Matthew D Robson, Hugh Watkins, Stefan Neubauer
2018 British Society of Cardiovascular Magnetic Resonance (BSCMR) Young Investigator Award Abstracts   unpublished
Introduction Disarray and fibrosis are a likely nidus for fatal arrhythmia in hypertrophic cardiomyopathy (HCM). These microstructural changes can be inferred by mapping the diffusion of water using diffusion tensor cardiac magnetic resonance (DT-CMR). Fractional anisotropy (FA) quantifies directionality of diffusion. We hypothesised that diastolic FA will be reduced in HCM and represents the arrhythmogenic substrate.
doi:10.1136/heartjnl-2018-bcvi.21 fatcat:exrygso2mrfh7g4jfq7pddl4ge