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When 3-methylcholanthrene therapy was initiated 8 days after transplantation of the myeloma X5568 in CgH mice, retardation and even complete suppression of the transplant resulted. It did not appear that a general depression of somatic growth eouM account for this effect. Histological examination of the carcinogen-treated myeloma revealed peripheral necrosis, reduction in mitotic figures, without a striking infiltration of leukocytes or normal plasma cells. Dihydrotestosterone in conjunctionpmid:13776591 fatcat:xrtgdgg7dfgr3boa267tjzrvla