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A synthetic, three-dimensional bone marrow hydrogel
[article]
2018
bioRxiv
pre-print
Three-dimensional (3D) synthetic hydrogels have recently emerged as desirable in vitro cell culture platforms capable of representing the extracellular geometry, elasticity, and water content of tissue in a tunable fashion. However, they are critically limited in their biological functionality. Hydrogels are typically decorated with a scant 1-3 peptide moieties to direct cell behavior, which vastly underrepresents the proteins found in the extracellular matrix (ECM) of real tissues. Further,
doi:10.1101/275842
fatcat:73e52k54pneptiypalrhbma3da