Chemical and photoelectron spectrometry analysis of the adsorption of phospholipid model membranes and red blood cell membranes on to chrysotile fibres

M C Jaurand, J H Thomassin, P Baillif, L Magne, J C Touray, J Bignon
1980 Occupational and Environmental Medicine  
A study of the interaction of phospholipid model membranes and red blood cell membranes with UICC A chrysotile fibres using chemical analysis and photoelectron spectrometry showed that the interaction agreed with an adsorption of the membranes on to the chrysotile fibres. The photoelectron spectrometry analysis allowed the statement that phospholipid model membranes are adsorbed as bilayer. Chemical analysis showed that for each milligram of chrysotile the amount of phospholipids adsorbed was
more » ... out 155 ,ug and the available surface for phospholipids was about 38 m2/g. It was established that entire membranes were adsorbed. A mechanism for the haemolytic capacity of chrysotile is suggested. Material and methods All experiments were carried out with UICC A chrysotile. Suspensions of the fibres were obtained by ultrasonic treatment at 20 KHz, power: 20 W for 45 s in KCl-NaCl 0d145 M. Human RBC and RBC on 22 July 2018 by guest. Protected by copyright.
doi:10.1136/oem.37.2.169 fatcat:j5z2ukhtmzao5gp2jqoyonlzse