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IDENTIFIKASI SENYAWA BAHAN ALAM SEBAGAI INHBITOR TIROSIN KINASE EGFR: SKRINING IN SILICO BERBASIS FARMAKOFOR DAN MOLECULAR DOCKING
2021
Jurnal fitofarmaka Indonesia
Epidermal growth factor receptor (EGFR) is one of tyrosine kinase that overexpressed in many types of cancer. The ihbiition of EGFR activity has known as a rational target for cancer therapy. However, several EGFR inhibitors have limitations related to resistance problems or reduced tumor response. Therefore, the effort to develop new inhibitors with greater efficacy is very important to overcome the problems. In the present study, we designed a computational method by combining ligand based
doi:10.33096/jffi.v8i1.539
fatcat:scgkhrksjvh7lhyphg6xnlmvjy